产品货号:
Z24092
中文名称:
PTGIS抗体
英文名称:
Anti-PTGIS Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PTGIS Antibody |
指标别名 | PTGIS;CYP8;CYP8A1;Prostacyclin synthase;EC 5.3.99.4;Prostaglandin I2 synthase |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,FCM,ELISA |
基因名称 | PTGIS |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human PTGIS/PGIS recombinant protein (Position:D119-D470). |
实际分子量 | 57KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Prostaglandin-I synthase (EC 5.3.99.4) also known as prostaglandin I2 (prostacyclin) synthase (PTGIS) or CYP8A1 is an enzyme involved in prostanoid biosynthesis that in humans is encoded by the PTGIS gene.This gene encodes a member of the cytochrome P450 superfamily of enzymes.The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol,steroids and other lipids.However,this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity.This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2),a potent vasodilator and inhibitor of platelet aggregation.An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction,stroke,and atherosclerosis. |
Uniprot ID | Q16647 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
基因名全称 | prostaglandin I2 synthase |
蛋白名全称 | Prostacyclin synthase |
推荐稀释比 | Western blot(WB) 1:500~2000 Flow cytometry (FCM) 1~3μg/1×106 cells ELISA 1:100~1000 |
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